自循环发酵过程周期性开关操控的设计和分析On/off operation design and analysis of a self-cycling fermentation process
吴思辰,翟持
摘要(Abstract):
针对乙醇间歇发酵生产速率低、劳动强度大,连续发酵会带来基质损失,甚至可能导致系统失稳的问题,探讨了一种能自动进行周期开关操控的自循环发酵(SCF)方案,并期望通过理论分析与设计来提高发酵过程的生产强度,同时消除产物抑制诱导系统失稳。具体地,从连续发酵模型稳定性分析出发,借助最优周期控制(OPC)理论给出SCF强化生产速率的必要性判据;进一步研究发现乙醇产物抑制作用会导致连续发酵系统失稳,并可有效缓解产物抑制作用,消除产物诱导失稳问题。模拟结果表明,生物乙醇的SCF生产模式可以缩短批次发酵时间、避免系统失稳。
关键词(KeyWords): 产物抑制失稳;最优周期控制;自循环发酵;提质增效
基金项目(Foundation): 云南省基础研究计划(202001AU070048)
作者(Author): 吴思辰,翟持
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