辛宇,阮建成,钱超,周少东,陈新志

• 1:浙江大学 化学工程与生物工程学院，浙江 杭州 310027

摘要(Abstract)：

工业上以天然羊毛脂为原料提取胆固醇的皂化反应通常在高压釜中进行，针对此过程存在反应时间长和安全风险高等问题，利用管道化反应器在线反应量小、维护成本低和传热传质效率高的特点，提出了安全、高效和可控的羊毛脂管道化皂化反应工艺，优化后的工艺条件为反应温度160℃、反应压力1.40 MPa、停留时间40 min，该条件下皂化收率为99.3%。皂化产物经过分离提纯可得到胆固醇、羊毛酸和羊毛醇，再将其中羊毛酸和羊毛醇通过酯化反应，再经过脱酸脱色处理后得到精制羊毛脂产品，从而获得更大的经济效益。

关键词(KeyWords)： 羊毛脂;皂化;管式反应器;酯化

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金（21476194）；国家重点研发计划（2016YFB0301800）。

作者(Author): 辛宇,阮建成,钱超,周少东,陈新志

DOI: 10.3969/j.issn.1003-9015.2021.05.013

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