刘迎新,李愈,方鑫,姚恩,魏作君

• 1:浙江工业大学药学院
• 2:浙江大学生物质化工教育部重点实验室浙江大学化学工程与生物工程学院
• 3:浙江大学衢州研究院

摘要(Abstract)：

为了解决果糖酸催化脱水制备5-羟甲基糠醛(5-HMF)及分离纯化过程中存在的低收率、低纯度等问题，提出低沸点溶剂中酸催化高浓度果糖生产5-HMF的方法，在此基础上，通过添加亚硫酸氢钠的饱和氯化钠溶液将反应液中5-HMF转化为易溶于水的磺酸钠盐，实现5-HMF与胡敏素等杂质的有效分离。结果表明，在四氢呋喃溶剂中，质量分数为24%的果糖在140℃下反应30 min,5-HMF最高收率达83.8%；采用亚硫酸氢钠分离工艺可得到工艺总收率为82.8%、纯度为95.1%的5-HMF。

关键词(KeyWords)： 果糖;5-羟甲基糠醛;胡敏素;亚硫酸氢钠;分离

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金(21878269,21476211);; 浙江省自然科学基金(LY18B060016)

作者(Author): 刘迎新,李愈,方鑫,姚恩,魏作君

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