超临界CO2流体萃取大黄游离蒽醌的研究Supercritical CO2 Extraction of Free Anthraquinones from Rheum Palmatum L.
未作君,林立,倪晋仁
摘要(Abstract)：
研究了带夹带剂的超临界流体萃取大黄中的五种有效蒽醌类物质(大黄酚、大黄素、芦荟大黄素、大黄酸和大黄素甲醚)的工艺,考察了萃取条件(温度和压力)、CO2流量、萃取时间、夹带剂种类等对大黄游离蒽醌萃取率的影响。通过正交实验对萃取釜条件(萃取压力、温度和夹带剂用量)进行了优化;采用液相色谱对萃取产物进行了分析。结果表明,分离釜的温度和压力、CO2流量等对萃取效率影响较小;最佳工艺条件为:静萃取时间为60min、动萃取时间为30min、以乙醇作夹带剂、乙醇用量300mL·(100g大黄)-1、萃取温度45°C、萃取压力45MPa。在此条件下大黄游离蒽醌的萃取量达1.15%。
关键词(KeyWords)： 超临界流体萃取;大黄;游离蒽醌;夹带剂
基金项目(Foundation):
作者(Author): 未作君,林立,倪晋仁
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