韦殿杰,李瑞,吴兆亮,赵艳丽

• 1:河北工业大学化工学院

摘要(Abstract)：

为了加强泡沫相排液,提高目的产物的富集比,设计了一种新型泡沫分离塔即泡沫相部分水平泡沫分离塔。以传统泡沫相垂直泡沫分离塔为对照塔,以牛血清蛋白(BSA)为体系,考察了表观气速、装液量、物料初始浓度和初始pH对牛血清蛋白(BSA)富集比和回收率的影响。结果表明泡沫相部分水平泡沫分离塔有效减小了泡沫相排液的阻力,提高了BSA的富集。在装液量为400 mL、初始浓度为0.2 g·L-1、pH为6.2和表观气速为19.1 m·h-1的条件下,泡沫相部分水平泡沫分离塔的富集比7.9是对照直塔的1.8倍。

关键词(KeyWords)： 泡沫分离;排液;错流;牛血清蛋白

Abstract:

Keywords:

基金项目(Foundation): 天津市应用基础及前沿技术研究计划重点资助项目(08JCZDJC25200);; 河北省自然科学基金资助项目(B2011202056)

作者(Author): 韦殿杰,李瑞,吴兆亮,赵艳丽

参考文献(References)：

• [1]Dube N M,Tzoneva R.Development of a mathematical model for ion exchage process for desalination of water[C].Lee Foundation,Singapore//IEEE,Montreal Section.Canadian Society of Mechanical Engineers,Fourth International Conference andAutomation.United States:Institute of Electrical and Electronics Inc,2003.723-727.
• [2]TAN Xiang-wei(谭相伟),WU Zhao-liang(吴兆亮),JIA Yong-sheng(贾永生),et al.Application of foam separation inmuliticomponent mixture of proteins(泡沫分离技术在蛋白质多元体系分离中的应用)[J].Chemical Industry and EngineeringProgress(化工进展),2005,24(5):510-513.
• [3]Paul S,Li X L,Geoffrey M E.A mechanism for internal reflux in foam fractionation[J].Biochem Eng,2008,39(3):590-593.
• [4]Lockwood C E,Bummer P M,Jay M.Purification of proteins using foam fractionation[J].Pharmaceut Res,1997,14(11):1511-1515.
• [5]QIAN Shao-yu(钱少瑜),LI Xue-liang(李雪良),WU Zhao-liang(吴兆亮),et al.Effects of total foam height on the liquid holdup inthe foam fractionation process(泡沫分离过程中泡沫层总高度对持液率的影响)[J].J Chem Eng of Chinese Univ(高校化学工程学报),2009,23(3):543-546.
• [6]Dickinson J E,Laskovski D,Stevenson P,et al.Enhanced foam drainage using parallel inclined channels in a single-stage foamfractionation column[J].Chem Eng Sci,2010,65(8):2481-2490.
• [7]SONG Wei-guang(宋伟光),WU Zhao-liang(吴兆亮),LIU Gui-min(刘桂敏),et al.Removal of trace metal ions from aqueoussolution by foam fractionation(泡沫分离除去水溶液中微量金属离子)[J].J Chem Eng of Chinese Univ(高校化学工程学报),2008,22(5):900-905.
• [8]Hossain M,Fenton G.Concentration of proteins from single component solution using a semi-batch foam process[J].Sep SciTechnol,1998,33(11):1703-1721.
• [9]Nopparat J F.Surfactant recovery from water using foam fractionation[J].Sep Sci Technol,1996,31(9):1233-1258.
• [10]HAN Bing,WU Zhao-liang,YIN Hao,et al.Study on streptomycin sulfate recovery by batch foam separation[J].Sep Sci Technol,2010,45(6):844-848.
• [11]Goutam Mukhopadhyay,Jasmina Khanam,Arunabha Nanda.Protein removal from whey waste by foam fractionation in a batchprocess[J].Sep Sci Technol,2010,45(9):1331-1339.
• [12]Saleh Zaid S,Hossain Md M.A study of the separation of proteins from multicomponent mixtures by a semi-batch foaming process[J].Chemical Engineering and Processing,2001,40(4):371-378.
• [13]Maruyama H,Suzuki A,Seki H,et al.Enrichment in axial direction of aqueous foam in continuous foam separation[J].BiochemEng J,2006,30(3):253-259.
• [14]Maruyama H,Seki H,Suzuki A,et al.Variation of saturated surface sensity of ovalbumin on bubble surface in continuous foamseparation[J].J Colloid Interface Sci,2006,299(1):416-420.
• [15]DONG Hong-xing(董红星),SUN Zhao-shen(孙兆申),PEI Jian(裴建),et al.Removal of chromium ion from water by using ferrouscoprecipitation foam separation(铁盐共沉淀泡沫分离法去除水中铬离子)[J].J Chem Ind and Eng(China)(化工学报),2006,57(9):2116-2122.
• [16]WANG Chang-ye(王创业).Study on Foam Fractionation of Proteins(泡沫分离法分离蛋白质的研究)[D].Tianjin(天津):TianjinUniversity(天津大学),2004.
• [17]Jeong G T,Park E S,Wahlig V L,et al.Effect of pH on the foam fractionation of mimosa pudica L.seed proteins[J].Ind EngChem Res,2004,43(2):422-427.
• [18]XU Zhong-he(徐钟河),WU Zhao-liang(吴兆亮),ZHAO Yan-li(赵艳丽).A preliminary investigation of protein adsorption behaviorin foam system with the presence of antifoam agent(消泡剂存在体系中蛋白质泡沫吸附行为的初探)[J].J Chem Eng of ChineseUniv(高校化学工程学报),2009,23(5):885-888.