任立伟,黄小玲,周华,韦萍

• 1:南京工业大学生物与制药工程学院

摘要(Abstract)：

以固定化酶Novozyme435为催化剂,在液-固混合体系中经酶催化1,4-丁二醇与丁二酸缩聚合成聚丁二酸丁二酯(PBS),考察反应条件对聚合效果的影响。采用GPC法对产物重均分子量Mw和分子量分布MwMn进行了测定;采用核磁共振法对产物结构进行了鉴定。最佳反应条件为:丁二酸与1,4-丁二醇的物质的量的比为17:23,Novozyme435用量为底物总质量的7%,聚合温度为65℃。以底物总质量200%的二苯醚为反应介质,真空条件下聚合48h,PBS的最大Mw可达到50800(MwMn=1.36)。实验表明,丁二酸在反应介质中的溶解程度和副产物水的去除是限制PBS聚合效果的最主要因素。

关键词(KeyWords)： 聚丁二酸丁二酯;PBS;丁二酸;Novozyme435;液-固反应

Abstract:

Keywords:

基金项目(Foundation): 国家重点基础研究发展计划资助(2009CB724701)

作者(Author): 任立伟,黄小玲,周华,韦萍

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