谭成侠,张谦

• 1:浙江工业大学化学工程与材料学院
• 2:浙江新和成股份有限公司 浙江杭州310014
• 3:浙江新昌312500

摘要(Abstract)：

以对氯苯甲醛和频哪酮为原料,经缩合、氢化、环氧化和开环反应合成杀菌剂戊唑醇。反应工艺选择了强碱性离子交换树脂为碱性催化剂以及采用CO2中和体系中的碱性物质,使4,4-二甲基-1-(4-对氯苯基)-1-戊烯-3-酮的收率达到98.3%,纯度达到97.4%;开环反应中利用1,2,4-三唑的两种异构体热力学稳定性差异,在强碱性离子交换树脂作用下使用了催化剂N,N-二甲基-4-氨基吡啶,使戊唑醇的纯度达到98.2%,收率达到67%以上。

关键词(KeyWords)： 戊唑醇;强碱性离子交换树脂;N,N-二甲基-4-氨基吡啶;合成

Abstract:

Keywords:

基金项目(Foundation): 国家自然基金资助项目(30500339)

作者(Author): 谭成侠,张谦

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