麻黄强化泡沫分离甘草酸的工艺研究Study on Ephedra Intensified Foam Fractionation of Glycyrrhizic Acid
丁琳琳,王延吉,吴兆亮,刘海倩,李瑞,刘伟
摘要(Abstract):
为了提高泡沫分离甘草中甘草酸的分离效果,开发了甘草麻黄配伍泡沫分离工艺,并就麻黄对浸提液泡沫性能的影响进行了研究。结果表明,麻黄强化了甘草酸的提取,但降低了浸提液中甘草苷的浓度,使得浸提液的泡沫性能发生变化而影响泡沫分离甘草酸的分离效果。以甘草酸的富集比和回收率为评价指标,研究了温度、气体体积流量、甘草酸初始浓度和甘草麻黄质量配比对分离效果的影响。结果表明当温度为40℃、气体体积流量为100 m L×min~(-1)、甘草酸初始浓度为0.2 g×L~(-1)和甘草麻黄质量配比为5:3时,获得甘草酸的富集比和回收率分别为8.34和62.5%。与单独泡沫分离甘草中甘草酸相比,甘草酸的富集比提高了121.7%,而回收率并未明显降低。因此,麻黄的引入有效地提高了泡沫分离甘草酸的分离效果。
关键词(KeyWords): 泡沫分离;甘草;甘草酸;麻黄
基金项目(Foundation): 国家自然科学基金(21236001);; 河北省重点基础研究项目(16964002D)
作者(Author): 丁琳琳,王延吉,吴兆亮,刘海倩,李瑞,刘伟
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