由乙醇和乙二醇直接法合成乙二醇单乙醚Synthesizing Ethylene Glycol Monoethyl Ether Directly from Ethanol and Ethylene Glycol
张栋,李刚森,章亚东
摘要(Abstract)：
以乙醇和乙二醇用直接法合成乙二醇单乙醚,探索了催化剂种类、反应温度、压力等因素对反应的影响,结果表明:以无水AlCl3为催化剂,乙二醇与乙醇的摩尔比为1:4,在240℃,压力7 MPa的条件下反应4 h,当催化剂用量为反应物总量的4%时,乙二醇的转化率35.8%,乙二醇单乙醚的选择性59.5%。通过单因素正交实验优化后,仍以无水AlCl3为催化剂,乙二醇与乙醇的摩尔比为1:4,在260℃,压力6 MPa的条件下反应4 h,乙二醇的转化率提高到38.8%,乙二醇单乙醚的选择性提高到59.9%。此外,考察了AlCl3/Na2HPO4复合催化剂在不同比例时对反应的影响。当无水AlCl3与Na2HPO4的摩尔比为1:3时,乙二醇的转化率为25.1%,乙二醇单乙醚的选择性为72.3%。
关键词(KeyWords)： 乙二醇单乙醚;直接合成法;乙醇;乙二醇;无水AlCl3
基金项目(Foundation):
作者(Author): 张栋,李刚森,章亚东
参考文献(References)：
- [1]CHEN Yong-fu(陈永福),QIN Yi-sheng(秦怡生).Market and production technology advances of ethylene glycol ether(乙二醇醚类的市场需求和生产技术进展)[J].Advances in Fine Petrochemicals(精细石油化工进展),2002,3(4):28-34.
- [2]WANG Yong-jie(王永杰),LI Wen-zhao(李文钊),LIU Jin-long(刘金龙).The process of glycol ether productive technology(乙二醇醚生产技术的进展)[J].Petrochemical Technology(石油化工),1999,28(3):58-61.
- [3]YU De-qi(于德起).Aspects and forecast about domestic ethylene glycol monoether production(国内乙二醇单醚的发展现状与预测)[J].Speciality Petrochemicals(精细石油化工),2002(5):49-54.
- [4]CHEN Neng-lin(程能林).Solvents handbook(溶剂手册)[M].Beijing(北京):Chemical Industry Press(化学工业出版社),2007.
- [5]LIU Ling-na(刘玲娜),ZHANG Qiang(张强).A review of the production technology and market profile on ethylene glycol ether(乙二醇醚生产技术及市场应用)[J].Chemical Intermediates(化工中间体),2012(5):24-27.
- [6]John F K.Process for preparing glycol ethers:US,18 693 380[P].1989-03-02.
- [7]Duggan D M.Catalysts and process for the dealkoxyhydroxymethylation of aetals to form glycol ethers:EU,85 304 436 A[P].1986-01-29.
- [8]William J B.Hydrogenolysis process for the production of monoethylene glycol monomethyl rther,monoethylene glycol and ethano:US,4 661 643[P].1987-04-28.
- [9]WANG Hai-bo(王海波).Preparation glycol ether with ethylene(一种由乙烯制取乙二醇单醚的方法):CN,102 452 908 A[P].2012-05-16.
- [10]Farahnaz K B,Majid M H,Hossien A O.Ferric perchlorate as an rfficient and useful catalyst for the selective benzylation and methylation of alcohols with benzyl chloride and methyl iodide[J].Monatshefte Für Chemie-Chemical Monthly,2009,140(2):181-184.
- [11]Tomoharu O,Yoshitaka A,Hideaki T,et al.Continuous chemoselective methylation of functionalized amines and diols with supercritical methanol over solid acid and acid-base bifunctional catalysts[J].American Chemical Society Journal,2004,126(23):7368-77.
- [12]Charles L Baimbridge.Method of producing glycol ethers:US,20 040 044 253 Al[P].2004-03-04.
- [13]FENG Cun-li(丰存礼).Production technology and market analysis of domestic ethylene glycol(国内乙二醇生产工艺技术情况与市场分析)[J].Chemical Industry and Engineering Progress(化工进展),2013,32(5):1200-1204.